Mercator Project

Supported by the Fritz-Thyssen Foundation

The adhesion GPCR GPR56 – a key regulator of lymphocyte cytotoxicity

Jörg Hamann, University of Amsterdam

Team members
Cheng-Chih Hsiao

Publications

Chang G-W, Hsiao C-C, Peng Y-M, Braga FAV, Kragten NAM, Remmerswaal EBM, van de Garde MDB, Straussberg R, König GM, Kostenis E, Knäuper V, Meyaard L, van Lier RAW, van Gisbergen KPJM, Lin H-H, and Hamann J (2016) The Adhesion G Protein-Coupled Receptor GPR56/ADGRG1 Is an Inhibitory Receptor on Human NK Cells. Cell Reports 15:1757-70. 

Hamann J, Hsiao CC, Lee CS, Ravichandran KS, Lin HH (2016) Adhesion GPCRs as Modulators of Immune Cell Function. Handbook of Experimental Pharmacology 234:329-350. 

Hamann J, Petrenko AG. Introduction: History of the Adhesion GPCR Field. Handbook of Experimental Pharmacology 234:1-11. 

Hsiao CC, Keysselt K, Chen HY, Sittig D, Hamann J, Lin HH, and Aust G (2015) The Adhesion GPCR CD97/ADGRE5 inhibits apoptosis. Int J Biochem Cell Biol 65:197-208.

Monk K, Hamann JLangenhan T, Nijmeijer S, Schöneberg T, and Liebscher I (2015) Adhesion GPCRs: From In Vitro Pharmacology to In Vivo Mechanisms. Molecular Pharmacology 88:617-623. Download_Icon 

Hamann J, Aust G, Arac D, Engel FB, Formstone C, Fredriksson R, Hall RA, Harty BL, Kirchhoff C, Knapp B, Krishnan A, Liebscher I, Lin H-H, Martinelli DC, Monk KR, Peeters MC, Piao X, Prömel S, Schöneberg T, Schwartz TW, Singer K, Stacey M, Ushkaryov YA, Vallon M, Wolfrum U, Wright MW, Xu L, Langenhan T, and Schiöth HB (2015) International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein-Coupled Receptors. Pharmacological Reviews 67:338–367.